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Type 2 diabetes is characterized by insulin resistance and progressive pancreatic beta-cell dysfunction, leading to relative insulin deficiency and hyperglycemia. Strongly associated with obesity, metabolic syndrome, and genetic predisposition. It presents with polyuria, polydipsia, polyphagia, and sometimes a skin condition called acanthosis nigricans. Chronic complications include atherosclerosis (leading to cardiovascular disease, stroke, and peripheral artery disease), retinopathy, nephropat
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