The brain is often referred to as a "black box"—one that's difficult to peer inside and determine what's happening at any given moment. This is part of the reason why it's difficult to understand the ...

The identification of genes involved in diseases is one of the major challenges of biomedical research. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have developed a ...

Creative Biogene's CRISPR library screening service is based on a multifaceted approach that includes designing personalized CRISPR libraries for specific gene families, cell lines, or disease models.

Recently, scientists have been able to explore gene circuitry in individual cells using methods that suppress particular genes and measure the impact on the expression of other genes. These methods, ...

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered ...

In this issue of BioTechniques, we present data from a validation study of a software tool for use in forensic investigative genetic genealogy and a method for producing hydrogel-based ‘transparent ...